Roma have both Daniele De Rossi and Patrik Schick in the squad to face Benevento, but have a decimated midfield.
It kicks off on Sunday at 19.45 GMT, click here for a match preview.
Both De Rossi and Schick remain serious doubts to start, but could be an option off the bench.
Coach Eusebio Di Francesco needs alternatives, because Radja Nainggolan and Lorenzo Pellegrini are suspended with Maxime Gonalons, Jonathan Silva and Rick Karsdorp injured.
Bruno Peres is dropped and fined after crashing his car while over the alcohol limit this week.
Roma squad for Benevento: Alisson, Skorupski, Lobont; Juan Jesus, Kolarov, Capradossi, Fazio, Florenzi, Bouah, Manolas; Strootman, De Rossi, Gerson, Riccardi, Marcucci; Perotti, Dzeko, Schick, Under, Defrel, El Shaarawy
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