Edin Dzeko and Stephan El Shaarawy are expected to be out for around three weeks, with the Roma pair aiming to return to face Juventus.
The Giallorossi are in the midst of an injury crisis, and they face Inter at the Stadio Olimpico on Sunday night.
Dzeko missed the Real Madrid defeat in midweek, while El Shaarawy had to be taken off after just 22 minutes.
According to Sky, both players are expected to be out for around three weeks, but could be back to face Juventus at the end of December.
Javier Pastore and Diego Perotti both returned to training yesterday, so should be in the squad to face the Nerazzurri, while Lorenzo Pellegrini may also be fit.
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