Cengiz Under, Patrik Schick and Rick Karsdorp are still out of action, as Roma named their squad to face Frosinone.
It kicks off on Sunday at 19.30 GMT, click here for a match preview.
Although Under has resumed training after his thigh strain, the Turkey international is not in the group travelling to the Stadio Benito Stirpe.
Schick and Karsdorp also miss out and remain behind to work on their fitness.
Roma squad for Frosinone: Olsen, Fuzato, Mirante, Juan Jesus, Kolarov, Marcano, Santon, Fazio, Florenzi, Manolas, Cristante, Pellegrini, De Rossi, Coric, Zaniolo, Pastore, Nzonzi, Perotti, Dzeko, Kluivert, El Shaarawy